CTSD

Name

cathepsin D

Type

protein-coding

Aliases

CLN10, CPSD, HEL-S-130P

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015].

via MyGene.info

Gene · Ensembl

cathepsin D

Symbol

CTSD

Biotype

Protein coding

Organism

Homo sapiens

Location

11:1,752,752-1,764,573

Strand

Reverse (−)

Assembly

GRCh38