clascoterone
Sign in to saveAlso known as 11-deoxycortisol 17α-propionate, Cortexolone 17α-propionate, CB-03-01, Breezula, Cortexolone 17alpha-propionate
Clascoterone, sold under the brand name Winlevi, is an antiandrogen medication which is used topically in the treatment of acne. The medication is used as a cream by application to the skin, for instance the face and scalp. Clascoterone is an antiandrogen, or antagonist of the androgen receptor (AR), the biological target of androgens such as testosterone and dihydrotestosterone. It shows minimal systemic absorption when applied to skin.
Key facts
- Drug.image
- Cortexolone 17α-propionate.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250
- Drug.tradename
- Winlevi
- Drug.DailyMedID
- Clascoterone
- Drug.pregnancy_AU
- D
- Drug.routes_of_administration
- Topical
- Drug.ATC_prefix
- D10
- Drug.ATC_suffix
- AX06
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.CAS_number
- 19608-29-8
- Drug.PubChem
- 11750009
- Drug.DrugBank
- DB12499
- Drug.ChemSpiderID
- 9924713
- Drug.UNII
- XN7MM8XG2M
- Drug.KEGG
- D11451
via Wikipedia infobox
~8 min read
Encyclopedic overview
16 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- History
- Society and culture
- Legal status
- Names
- Research
- Scalp hair loss
- Other uses
- See also
- References
- External links
Clascoterone, sold under the brand name Winlevi, is an antiandrogen medication which is used topically in the treatment of acne. The medication is used as a cream by application to the skin, for instance the face and scalp. Clascoterone is an antiandrogen, or antagonist of the androgen receptor (AR), the biological target of androgens such as testosterone and dihydrotestosterone. It shows minimal systemic absorption when applied to skin.
Clascoterone was developed by Cassiopea and was approved for medical use in the United States in August 2020 and in the European Union in October 2025. The US Food and Drug Administration (FDA) considers it to be a first-in-class medication.
Excerpted from Wikipedia’s “clascoterone” article, available under the CC BY-SA 4.0 licence.