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complementarity determining region
Sign in to saveAlso known as Complementarity-determining regions
part of the variable chains in immunoglobulins (antibodies) and T cell receptors, generated by B-cells and T-cells respectively
Research
5,746 papers- Downsizing antibodies: Towards complementarity-determining region (CDR)-based peptide mimetics.Bioorganic chemistry · 2022
- Complementarity-determining region clustering may cause CAR-T cell dysfunction.Nature communications · 2023
- IGH Complementarity Determining Region-3-Cytomegalovirus Protein Chemical Complementarity Linked to Better Overall Survival Probabilities for Glioblastoma.Viral immunology · 2024
- Antibody complementarity determining region design using high-capacity machine learning.Bioinformatics (Oxford, England) · 2020
- In vitro affinity maturation of HuCAL antibodies: complementarity determining region exchange and RapMAT technology.Immunotherapy · 2009
via PubMed
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Connections
antibody
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T-cell receptor
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International Standard Book Number
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digital object identifier
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Q180686
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lymphocyte
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hydrogen bond
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T-lymphocytes
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bibcode
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B-cell
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Q229883
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Medical Subject Headings
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monoclonal antibody
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Protein Data Bank
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protein primary structure
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protein tertiary structure
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immunoglobulin M
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paratope
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fragment antigen-binding
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immunoglobulin light chain
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