conjugated estrogens
Sign in to saveAlso known as Cenestin, Enjuvia, Premarin, Conestoral, Estrogens, Hyhorin, Estrogenic substances (conjugated), Evex
complex mixture of sodium estrone sulfate and sodium equilin sulfate derived synthetically from estrone and equilin from horse urine
Medication
- Generic name
- Estrogens, Conjugated
- Brand names
- Premarin
- Drug class
- Estrogen, Estrogen Receptor Agonists
- Route
- Oral
- Type
- Human Prescription Drug
- Manufacturer
- Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.
Indications: 1 INDICATIONS AND USAGE PREMARIN is a mixture of estrogens indicated for: • Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause ( 1.1 ) • Treatment of Moderate to Severe Vulvar and Vaginal Atrophy due to Menopause ( 1.2 ) • Treatment of Hypoestrogenism due to Hypogonadism, Castrat… (per FDA label)
Sources: openFDA · RxNorm (NLM). Not medical advice.
Research
5,236 papers- Bazedoxifene plus conjugated estrogens improve menopausal symptoms in postmenopausal women: a systematic review and meta-analysis.Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2022
- Conjugated Estrogens/Bazedoxifene (Duavee) for Menopausal Symptoms.American family physician · 2016
- Conjugated estrogens--the natural SERMs.Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 1999
- Conjugated estrogens and breast cancer risk.Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 1999
- Conjugated estrogens and hypercoagulability.American journal of obstetrics and gynecology · 1975
via PubMed
Clinical Trials
58 registered- PHASE1COMPLETEDStudy Comparing 3 New Formulations of Premarin® 0.625 mg/MPA 2.5 mg With a Reference FormulationWyeth is now a wholly owned subsidiary of Pfizer · NCT00630435
- PHASE1COMPLETEDA Study To Compare The Amount Of Premarin Components That Is Absorbed Into The Blood Of Japanese Healthy Postmenopausal Women Following Oral Administration Of Two Different Tablets Of Premarin Under Fast and Fed Conditions.Pfizer · NCT01436513
- UNKNOWNCorrelation of Non-invasive CPM Wearable Device With Measures of Congestion in Heart Failure in ExerciseNHS Greater Glasgow and Clyde · NCT06393842
- PHASE1RECRUITINGAffect of Duavive on Mood & Anxiety SymptomsSt. Joseph's Healthcare Hamilton · NCT04478305
- PHASE1COMPLETEDStudy Evaluating Effects of Multiple-Dose Administration of Itraconazole on the Single Dose Pharmacokinetics of Conjugated Estrogens/Bazedoxifene in Non-Obese and Obese Postmenopausal WomenPfizer · NCT02100553
- PHASE3COMPLETEDTibolone Endometrium Study (Study 32972)(P06470)Organon and Co · NCT00745108