Structure via PubChem · Public domain (PubChem)
flibanserin
Sign in to saveAlso known as Addyi®, BIMT-17, Girosa® (proposed trade name), 1-(2-(4-alpha,alpha,alpha-Trifluoro-m-tolyl)-1-(piperazinyl)ethyl)-2-benzimidazolinone, Female Viagra (Street Name), Bimt 17, 1,3-Dihydro-1-(2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl)-2H-benzimidazol-2-one, BIMT 17 BS
Flibanserin, sold under the brand name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD). The medication attempts to improve sexual desire, increase the number of satisfying sexual events, and decrease the distress associated with low sexual desire. The most common side effects are dizziness, sleepiness, nausea, difficulty falling asleep or staying asleep and dry mouth.
Key facts
- Drug.PubChem
- 6918248
- Drug.UNII
- 37JK4STR6Z
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 437139289
- Drug.image
- Flibanserin.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Flibanserin ball-and-stick model.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Addyi
- Drug.MedlinePlus
- a615040
- Drug.DailyMedID
- Flibanserin
- Drug.routes_of_administration
- By mouth
- Drug.ATC_prefix
- G02
- Drug.ATC_suffix
- CX02
- Drug.legal_US
- Rx-only
- Drug.bioavailability
- 33%
- Drug.protein_bound
- ~98%
via Wikipedia infobox
Chemical data
- Formula
- C20H21F3N4O
- Molecular weight
- 390.4 g/mol
- IUPAC name
- 3-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one
- SMILES
- C1CN(CCN1CCN2C3=CC=CC=C3NC2=O)C4=CC=CC(=C4)C(F)(F)F
- InChIKey
- PPRRDFIXUUSXRA-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 38.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Research
274 papers- Flibanserin.Journal of pharmacy practice · 2017
- Flibanserin and its discontents.Archives of women's mental health · 2017
- Flibanserin Therapy and CYP2C19 Genotype.2012
- Evaluation of safety for flibanserin.Expert opinion on drug safety · 2020
- Flibanserin.2012
via PubMed
Wikidata facts
- Mass
- 390.167
Show 4 more facts
- chemical formula
- C₂₀H₂₁F₃N₄O
- canonical SMILES
- C1CN(CCN1CCN2C3=CC=CC=C3NC2=O)C4=CC=CC(=C4)C(F)(F)F
- World Health Organisation international non-proprietary name
- flibanserin
- Commons category
- Flibanserin
via Wikidata · CC0
~13 min read
Article
13 sectionsContents
- Medical uses
- Side effects
- Mechanism of action
- Activity profile
- Society and culture
- Names
- Approval process and advocacy
- Advocacy groups
- Acquisition by Valeant Pharmaceuticals
- Reception
- References
- Further reading
- External links
{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 437139289 | image = Flibanserin.svg | image_class = skin-invert-image | alt = | image2 = Flibanserin ball-and-stick model.png | image_class2 = bg-transparent | alt2 =
| pronounce = | tradename = Addyi | Drugs.com = | MedlinePlus = a615040 | DailyMedID = Flibanserin | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | class = | ATC_prefix = G02 | ATC_suffix = CX02