Also known as steroid 5beta-reductase, cortisone delta4-5beta-reductase, delta(4)-hydrogenase, cholestenone 5b-reductase, testosterone 5beta-reductase, androstenedione 5-beta-reductase, delta4-5beta-reductase, 4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase
5β-Reductase, or Δ4-3-oxosteroid 5β-reductase (, 3-oxo-Δ4-steroid 5β-reductase, androstenedione 5β-reductase, cholestenone 5β-reductase, cortisone 5β-reductase, cortisone Δ4-5β-reductase, steroid 5β-reductase, testosterone 5β-reductase, Δ4-3-ketosteroid 5β-reductase, Δ4-5β-reductase, Δ4-hydrogenase, 4,5β-dihydrocortisone:NADP+ Δ4-oxidoreductase, 3-oxo-5β-steroid:NADP+ Δ4-oxidoreductase) is an enzyme with systematic name 5β-cholestan-3-one:NADP+ 4,5-oxidoreductase.
5β-Reductase, or Δ4-3-oxosteroid 5β-reductase (, 3-oxo-Δ4-steroid 5β-reductase, androstenedione 5β-reductase, cholestenone 5β-reductase, cortisone 5β-reductase, cortisone Δ4-5β-reductase, steroid 5β-reductase, testosterone 5β-reductase, Δ4-3-ketosteroid 5β-reductase, Δ4-5β-reductase, Δ4-hydrogenase, 4,5β-dihydrocortisone:NADP+ Δ4-oxidoreductase, 3-oxo-5β-steroid:NADP+ Δ4-oxidoreductase) is an enzyme with systematic name 5β-cholestan-3-one:NADP+ 4,5-oxidoreductase.
This enzyme catalyses the following general chemical reaction: 5β-cholestan-3-one + NADP+ \rightleftharpoons cholest-4-en-3-one + NADPH + H+
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).