File:Finasteride.svg · Wikimedia Commons · See Wikimedia Commons
finasteride
Sign in to saveAlso known as MK 906, MK-906, MK906, (5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used to treat pattern hair loss and benign prostatic hyperplasia (BPH). It can also be used to treat excessive hair growth in women. It is usually taken orally but there are topical formulations for patients with hair loss, designed to minimize systemic exposure by acting specifically on hair follicles.
OverviewAI-generated
Finasteride is a chemical compound with the formula C₂₃H₃₆N₂O₂. Its molecular mass is listed as 372.278, while its weight is recorded as 372.5. The substance has a defined daily dose of 5.
Chemical properties include an xlogp value of 3 and a topological polar surface area of 58.2. The molecule contains two hydrogen bond donors and two hydrogen bond acceptors, with a charge of 0. It is associated with a PubMed query count of 4080 and is referenced by 465 other encyclopedia articles.
Synthesized by Vinony from 18 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 458461973
- Drug.image
- Finasteride.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.image2
- Finasteride-from-xtal-3D-bs-17.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 250
- Drug.tradename
- Proscar, Propecia, Finide, others
- Drug.MedlinePlus
- a698016
- Drug.DailyMedID
- Finasteride
- Drug.pregnancy_AU
- X
- Drug.routes_of_administration
- By mouth, topical
- Drug.class
- 5α-Reductase inhibitor
- Drug.ATC_prefix
- G04
- Drug.ATC_suffix
- CB01
- Drug.legal_AU
- S4
- Drug.legal_CA
- Rx-only
via Wikipedia infobox
Chemical data
- Formula
- C23H36N2O2
- Molecular weight
- 372.5 g/mol
- IUPAC name
- (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
- SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC(C)(C)C)CC[C@@H]4[C@@]3(C=CC(=O)N4)C
- InChIKey
- DBEPLOCGEIEOCV-WSBQPABSSA-N
- XLogP
- 3
- Polar surface area
- 58.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
4,080 papers- Comparison of oral minoxidil, finasteride, and dutasteride for treating androgenetic alopecia.The Journal of dermatological treatment · 2022
- Finasteride for hair loss: a review.The Journal of dermatological treatment · 2022
- Efficacy and safety of topical finasteride spray solution for male androgenetic alopecia: a phase III, randomized, controlled clinical trial.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022
- Risk of Depression Associated With Finasteride Treatment.Journal of clinical psychopharmacology · 2021
- Sexual side effects of 5-α-reductase inhibitors finasteride and dutasteride: A comprehensive review.Dermatology online journal · 2017
via PubMed
~24 min read
Encyclopedic overview
26 sectionsContents
- Medical uses
- Enlarged prostate
- Pattern hair loss
- Prostate cancer
- Excessive hair growth
- Adverse effects
- Sexual adverse effects
- Finasteride for androgenetic alopecia (hair loss in men)
- Finasteride for benign prostatic hyperplasia
- Long-term
- Post-finasteride syndrome
- Overdose
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Synthesis
- History
- Society and culture
- Generic names
- Brand names
- Athletics
- Miscellaneous
- Research
- References
Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used to treat pattern hair loss and benign prostatic hyperplasia (BPH). It can also be used to treat excessive hair growth in women. It is usually taken orally but there are topical formulations for patients with hair loss, designed to minimize systemic exposure by acting specifically on hair follicles.
Finasteride is a 5α-reductase inhibitor and therefore an antiandrogen. It works by decreasing the production of dihydrotestosterone (DHT) by about 70%.
Excerpted from Wikipedia’s “finasteride” article, available under the CC BY-SA 4.0 licence.