hydroxyprogesterone caproate

Chemical data

Formula

C27H40O4

Molecular weight

428.6 g/mol

IUPAC name

[(8R,9S,10R,13S,14S,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] hexanoate

SMILES

CCCCCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)C(=O)C

InChIKey

DOMWKUIIPQCAJU-LJHIYBGHSA-N

XLogP

5.7

Polar surface area

60.4 Ų

H-bond donors

0

H-bond acceptors

4

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

1975

Admin. routes

parenteral

Indications

premature birth, pregnancy

via ChEMBL · EBI

• 17α-Hydroxyprogesterone Caproate and the Risk of Glucose Intolerance in Pregnancy: A Systematic Review and Meta-analysis.Obstetrics and gynecology · 2019
• Adjuvant 17-hydroxyprogesterone caproate in women withultrasound-indicated cerclage: a systematic review and meta-analysis.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2020
• 17-alpha hydroxyprogesterone caproate for preterm birth prevention: Where have we been, how did we get here, and where are we going?Seminars in perinatology · 2017
• Adjuvant 17-hydroxyprogesterone caproate in women with history-indicated cerclage: A systematic review and meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2019
• 17 Alpha-hydroxyprogesterone caproate use in a rural state.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2022

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

428.29266

Has use

medication

via Wikidata · CC0