Cosimo Rosselli

Nativity, 1490s. Amsterdam, Rijksmuseum. Handing over the Tablets of the Law, Sistine Chapel Madonna and Child with Angels, ca 1481. New York, Metropolitan Museum of Art. Cosimo Rosselli ( Italian: [ˈkɔːzimo rosˈsɛlli]; 1439–1507) was an Italian painter of the Quattrocento, active mainly in his birthplace of Florence, but also in Pisa earlier in his career and in 1481–82 in the Sistine Chapel in Rome, where he painted some of the large frescoes on the side walls.

Though generally regarded as a lesser talent in comparison to Sandro Botticelli, Pietro Perugino, and Domenico Ghirlandaio, who were all also active at the Sistine Chapel, Rosselli was still able to win large and important commissions throughout his career, a testament to his high level of activity in his native Florence. Important local commissions include a fresco in the cloister of Santissima Annunziata, Florence and those in the Chapel of the Holy Blood in Sant'Ambrogio, Florence.