CPA6
Sign in to saveAlso known as CPAH, ETL5, FEB11, carboxypeptidase A6
protein-coding gene in the species Homo sapiens
Gene data
CPA6- Name
- carboxypeptidase A6
- Type
- protein-coding
- Position
- 67,421,106–67,746,378 (−)
- Aliases
- CPAH, ETL5, FEB11
- Ensembl
- ENSG00000165078
- RefSeq RNA
- NM_001127445.1, NM_001440615.1, NM_020361.5, XM_017013646.2, XM_054360856.1
- RefSeq protein
- NP_001427544.1, NP_065094.3, XP_016869135.1, XP_054216831.1
The gene encodes a member of the peptidase M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which catalyzes the release of large hydrophobic C-terminal amino acids. This enzyme has functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Mutations in this gene may be linked to epilepsy and febrile seizures, and a translocation t(6;8)(q26;q13) involving this gene has been associated with Duane retraction syndrome. [provided by RefSeq, May 2016].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
carboxypeptidase A6
- Symbol
- CPA6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:67,421,106-67,746,378
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI