File:Creatinine-tautomerism-2D-skeletal.svg · Wikimedia Commons · See Wikimedia Commons
creatina
Sign in to saveAlso known as Kreatin, (α-methylguanido)acetic acid, N-(aminoiminomethyl)-N-methylglycine, Methylglycocyamine, N-Amidinosarcosine, N-Carbamimidoyl-N-methylglycine, (N-methylcarbamimidamido)acetic acid, alpha-Methylguanidino acetic acid
farmaco
OverviewAI-generated
Creatine is a chemical compound with the formula C₄H₉N₃O₂. Its IUPAC name is 2-[carbamimidoyl(methyl)amino]acetic acid. The substance has a mass of 131.069 and a weight of 131.13. It possesses a charge of 0, an xlogp of -1.2, and a tpsa of 90.4. The molecule contains three hydrogen bond donors and three hydrogen bond acceptors.
In food products, creatine is categorized with a nutriscore of a and a nova classification of 4. Nutritional data for these products indicates an energy value of 21 kcal, 0 fat, 0.6 carbohydrates, 0.2 sugars, 0 fiber, 4.3 proteins, and 0.04 salt. There are seven products listed in this category.
The term creatine appears in 72,188 PubMed records. Additionally, the subject is referenced by 486 other encyclopedia articles.
Synthesized by Vinony from 29 facts across 5 sources: Wikidata, PubChem, PubMed, Openfoodfacts, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- C4H9N3O2
- Molecular weight
- 131.13 g/mol
- IUPAC name
- 2-[carbamimidoyl(methyl)amino]acetic acid
- SMILES
- CN(CC(=O)O)C(=N)N
- InChIKey
- CVSVTCORWBXHQV-UHFFFAOYSA-N
- XLogP
- -1.2
- Polar surface area
- 90.4 Ų
- H-bond donors
- 3
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- ulcerative colitis, muscular disease, chronic fatigue syndrome, sarcopenia
via ChEMBL · EBI
Nutrition · Open Food Facts
Typical values per 100 g · averaged across 7 products
- Energy
- 21 kcal
- Fat
- 0 g
- — of which saturates
- 0 g
- Carbohydrates
- 0.6 g
- — of which sugars
- 0.2 g
- Fibre
- 0 g
- Protein
- 4.3 g
- Salt
- 0.04 g
via Open Food Facts · ODbL
Research
72,188 papers- Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?ReviewJournal of the International Society of Sports Nutrition · 2021Antonio J, Candow DG, Forbes SC et al.DOI: 10.1186/s12970-021-00412-w
- Creatine in Health and Disease.Nutrients · 2021Kreider RB, Stout JRDOI: 10.3390/nu13020447
- Effects of Creatine Supplementation on Brain Function and Health.ReviewNutrients · 2022Forbes SC, Cordingley DM, Cornish SM et al.DOI: 10.3390/nu14050921
- Creatine Use in Sports.ReviewSports health · 2018Butts J, Jacobs B, Silvis MDOI: 10.1177/1941738117737248
- "Heads Up" for Creatine Supplementation and its Potential Applications for Brain Health and Function.ReviewSports medicine (Auckland, N.Z.) · 2023Candow DG, Forbes SC, Ostojic SM et al.DOI: 10.1007/s40279-023-01870-9
- Creatine and multiple sclerosis.ReviewNutritional neuroscience · 2022Ostojic SMDOI: 10.1080/1028415X.2020.1819108
- The two sides of creatine in cancer.ReviewTrends in cell biology · 2022Zhang L, Bu PDOI: 10.1016/j.tcb.2021.11.004
- Creatine supplementation and endurance performance: surges and sprints to win the race.ReviewJournal of the International Society of Sports Nutrition · 2023Forbes SC, Candow DG, Neto JHF et al.DOI: 10.1080/15502783.2023.2204071
via PubMed
Wikidata facts
- Subclass of
- amino acid
- Has part
- carbon
- Mass
- 131.069
- Has use
- bodybuilding supplement
Show 6 more facts
- found in taxon
- soybean
- Commons category
- Creatine
- chemical formula
- C₄H₉N₃O₂
- canonical SMILES
- CN(CC(=O)O)C(=N)N
- different from
- creatinine
- has characteristic
- bitterness
Sources (10)
via Wikidata · CC0
Article · Italiano
La creatina (dal greco κρέας, krèas, "carne") è un derivato amminoacidico che può essere sintetizzato dal fegato (1 g/die) a partire da arginina, S-adenosil metionina e glicina, ed è utilizzato nei muscoli dei mammiferi per rigenerare ATP durante i primi secondi della contrazione muscolare. L'organismo umano è in grado di immagazzinarne al massimo 0,3 g per ogni kg di peso corporeo. Quando si assume creatina di origine animale, si ha la sua fosforilazione sull'azoto non glicinico a fosfocreatina. Normalmente viene ricercato il suo prodotto di degradazione nelle urine e nel sangue, la creatinina, attraverso un esame chiamato creatininemia, come indice della funzionalità renale. Viene impiegata nella terapia medica e come integratore utilizzato dagli sportivi soprattutto in discipline anaerobiche, come ad esempio culturismo, sollevamento pesi e simili.
Abstract from DBpedia / Wikipedia · CC BY-SA