Dactolisib (codenamed NVP-BEZ235 and BEZ-235, also known as RTB101) is an imidazoquinoline derivative acting as a PI3K inhibitor. It also inhibits mTOR. It is being investigated as a possible cancer treatment.
{{Chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 458976997 | ImageFile = Dactolisib.svg | ImageClass = skin-invert-image | ImageSize = 220px | ImageFile1 = Dactolisib molecule ball.png | ImageClass1 = bg-transparent | ImageSize1 = 240 | ImageAlt1 = Ball-and-stick model of the BEZ235 molecule | PIN = 2-Methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile | OtherNames = NVP-BEZ235; BEZ-235; RTB101
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).