DGCR8
Sign in to saveAlso known as C22orf12, DGCRK6, Gy1, pasha, Pasha, DGCR8 microprocessor complex subunit, DGCR8, microprocessor complex subunit
protein-coding gene in the species Homo sapiens
Gene data
DGCR8- Name
- DGCR8 microprocessor complex subunit
- Type
- protein-coding
- Position
- 20,080,025–20,111,877 (+)
- Aliases
- C22orf12, DGCRK6, Gy1, pasha
- Ensembl
- ENSG00000128191
- RefSeq RNA
- NM_001190326.2, NM_022720.7, XM_006724268.4, XM_047441418.1, XM_047441419.1
- RefSeq protein
- NP_001177255.1, NP_073557.3, XP_006724331.1, XP_047297374.1, XP_047297375.1
This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
DGCR8 microprocessor complex subunit
- Symbol
- DGCR8
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:20,080,025-20,111,877
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein DGCR8 PDB 1x47.png
Show 7 more facts
- HomoloGene ID
- 11223
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/54487
- genomic end
- 20099400
- genomic start
- 20067755
- chromosome
- human chromosome 22
- cytogenetic location
- 22q11.21
Sources (3)
via Wikidata · CC0