Structure via PubChem · Public domain (PubChem)
diminazene
Sign in to saveAlso known as 1,3-TRIS-(4'AMIDINOPHENYL)TRIAZINE, 4,4'-(1-Triazene-1,3-diyl)bis-benzenecarboximidamide, 4,4'-(Diazoamino)benzamidine, Diminazine, Diminazine aceturate, Diminazene aceturate
Diminazene (INN; also known as diminazen) is an anti-infective medication for animals that is sold under a variety of brand names. It is effective against certain protozoa such as Babesia, Trypanosoma, and Cytauxzoon. The drug may also be effective against certain bacteria including Brucella and Streptococcus.
Chemical data
- Formula
- C14H15N7
- Molecular weight
- 281.32 g/mol
- IUPAC name
- 4-[2-(4-carbamimidoylphenyl)iminohydrazinyl]benzenecarboximidamide
- SMILES
- C1=CC(=CC=C1C(=N)N)NN=NC2=CC=C(C=C2)C(=N)N
- InChIKey
- XNYZHCFCZNMTFY-UHFFFAOYSA-N
- XLogP
- 1.9
- Polar surface area
- 136 Ų
- H-bond donors
- 5
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
1,121 papers- Pharmacology of diminazene: a review.Acta tropica · 1993
- Diminazene aceturate--An antiparasitic drug of antiquity: Advances in pharmacology & therapeutics.Pharmacological research · 2015
- Diminazene aceturate (Berenil), a new use for an old compound?International immunopharmacology · 2014
- Diminazene aceturate uses different pathways to induce relaxation in healthy and atherogenic blood vessels.Biochemical pharmacology · 2023
- Diminazene aceturate mitigates cardiomyopathy by interfering with renin-angiotensin system in a septic rat model.BMC pharmacology & toxicology · 2022
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 281.139
Show 5 more facts
- chemical formula
- C₁₄H₁₅N₇
- canonical SMILES
- C1=CC(=CC=C1C(=N)N)NN=NC2=CC=C(C=C2)C(=N)N
- isomeric SMILES
- C1=CC(=CC=C1C(=N)N)N/N=N/C2=CC=C(C=C2)C(=N)N
- World Health Organisation international non-proprietary name
- diminazene
- Commons category
- Diminazene
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Side effects
- Resistance
- References
Diminazene (INN; also known as diminazen) is an anti-infective medication for animals that is sold under a variety of brand names. It is effective against certain protozoa such as Babesia, Trypanosoma, and Cytauxzoon. The drug may also be effective against certain bacteria including Brucella and Streptococcus.
Chemically it is a di-amidine and it is formulated as its aceturate salt, diminazene aceturate.
Excerpted from Wikipedia’s “diminazene” article, available under the CC BY-SA 4.0 licence.