File:Hybridogenesis_in_water_frogs_gametes.svg · Wikimedia Commons · See Wikimedia Commons
DNA sequencing
Sign in to saveAlso known as sequence analysis, DNA, DNA sequence analysis
technique in molecular biology
Research
595,314 papers- Applications of Single-Cell DNA Sequencing.Annual review of genomics and human genetics · 2021
- DNA Sequencing Sensors: An Overview.Sensors (Basel, Switzerland) · 2017
- DNA sequencing: the key to unveiling genome.Science China. Life sciences · 2020
- Nanopore DNA sequencing technologies and their applications towards single-molecule proteomics.Nature chemistry · 2024
- DNA sequencing.The Proceedings of the Nutrition Society · 1996
via PubMed
~40 min read
Encyclopedic overview
DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, thymine, cytosine, and guanine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery.
Knowledge of DNA sequences has become indispensable for basic biological research, DNA Genographic Projects and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics. Comparing healthy and mutated DNA sequences can diagnose different diseases including various cancers, characterize antibody repertoire, and can be used to guide patient treatment. Having a quick way to sequence DNA allows for faster and more individualized medical care to be administered, and for more organisms to be identified and cataloged.
Excerpted from Wikipedia’s “DNA sequencing” article, available under the CC BY-SA 4.0 licence.