DOC2A
Sign in to saveAlso known as Doc2, double C2 domain alpha
Double C2-like domain-containing protein alpha is a protein that in humans is encoded by the DOC2A gene.
Gene data
DOC2A- Name
- double C2 domain alpha
- Type
- protein-coding
- Position
- 30,005,507–30,023,270 (−)
- Aliases
- Doc2
- Ensembl
- ENSG00000149927
- RefSeq RNA
- NM_001282062.1, NM_001282063.2, NM_001282068.2, NM_003586.3, NR_104089.2
- RefSeq protein
- NP_001268991.1, NP_001268992.1, NP_001268997.1, NP_003577.2, XP_047290758.1
There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
double C2 domain alpha
- Symbol
- DOC2A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:30,005,507-30,023,270
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 2657
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8448
- genomic end
- 30034591
- genomic start
- 30005514
- chromosome
- human chromosome 16
- cytogenetic location
- 16p11.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Double C2-like domain-containing protein alpha is a protein that in humans is encoded by the DOC2A gene.
There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.
Excerpted from Wikipedia’s “DOC2A” article, available under the CC BY-SA 4.0 licence.