Gene data
DOC2A- Name
- double C2 domain alpha
- Type
- protein-coding
- Position
- 30,005,507–30,023,270 (−)
- Aliases
- Doc2
- Ensembl
- ENSG00000149927
- RefSeq RNA
- NM_001282062.1, NM_001282063.2, NM_001282068.2, NM_003586.3, NR_104089.2
- RefSeq protein
- NP_001268991.1, NP_001268992.1, NP_001268997.1, NP_003577.2, XP_047290758.1
There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].
Gene Ontology
Biological process
chemical synaptic transmissionchemical synaptic transmissionnervous system developmentsynaptic vesicle exocytosisregulation of calcium ion-dependent exocytosisregulation of calcium ion-dependent exocytosispositive regulation of calcium ion-dependent exocytosiscalcium-dependent activation of synaptic vesicle fusion
Molecular function
via MyGene.info
Gene · Ensembl
double C2 domain alpha
- Symbol
- DOC2A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:30,005,507-30,023,270
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 2657
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8448
- genomic end
- 30034591
- genomic start
- 30005514
- chromosome
- human chromosome 16
- cytogenetic location
- 16p11.2
Sources (3)
via Wikidata · CC0