DPM3
Sign in to saveAlso known as CDG1O, dolichyl-phosphate mannosyltransferase subunit 3, dolichyl-phosphate mannosyltransferase subunit 3, regulatory, MDDGB15, MDDGC15
dolichyl-phosphate mannosyltransferase polypeptide 3, also known as DPM3, is a human gene.
Gene data
DPM3- Name
- dolichyl-phosphate mannosyltransferase subunit 3, regulatory
- Type
- protein-coding
- Position
- 155,138,457–155,140,595 (−)
- Aliases
- CDG1O, MDDGB15, MDDGC15
- Ensembl
- ENSG00000179085
- RefSeq RNA
- NM_018973.4, NM_153741.2, XM_017001498.2, XM_054337104.1
- RefSeq protein
- NP_061846.2, NP_714963.1, XP_016856987.1, XP_054193079.1
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Pathways
via MyGene.info
Gene · Ensembl
dolichyl-phosphate mannosyltransferase subunit 3, regulatory
- Symbol
- DPM3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:155,138,457-155,140,595
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- References
- Further reading
- External links
dolichyl-phosphate mannosyltransferase polypeptide 3, also known as DPM3, is a human gene.
== Function ==
Excerpted from Wikipedia’s “DPM3” article, available under the CC BY-SA 4.0 licence.