UGT2B17
Sign in to saveAlso known as BMND12, UDPGT2B17, UDP glucuronosyltransferase family 2 member B17
UDP-glucuronosyltransferase 2B17 is an enzyme that in humans is encoded by the UGT2B17 gene.
Gene data
UGT2B17- Name
- UDP glucuronosyltransferase family 2 member B17
- Type
- protein-coding
- Position
- 68,516,301–68,627,039 (−)
- Aliases
- BMND12, UDPGT2B17
- Ensembl
- ENSG00000197888
- RefSeq RNA
- NM_001077.4
- RefSeq protein
- NP_001068.1
This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis.[provided by RefSeq, Apr 2010].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
UDP glucuronosyltransferase family 2 member B17
- Symbol
- UGT2B17
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:68,516,301-68,627,039
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
UDP-glucuronosyltransferase 2B17 is an enzyme that in humans is encoded by the UGT2B17 gene.
UGT2B17 belongs to the family of UDP-glucuronosyltransferases (UGTs; EC 2.4.1.17), enzymes that catalyze the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a variety of substrates, including steroid hormones.[supplied by OMIM] It also metabolizes 3-hydroxycotinine, which is minor nicotine metabolite ==References==
Excerpted from Wikipedia’s “UGT2B17” article, available under the CC BY-SA 4.0 licence.