Gene data
DUSP22- Name
- dual specificity phosphatase 22
- Type
- protein-coding
- Position
- 291,630–369,379 (+)
- Aliases
- JKAP, JSP-1, JSP1, LMW-DSP2, LMWDSP2, MKP-x, MKPX, VHX
- Ensembl
- ENSG00000112679
- RefSeq RNA
- NM_001286555.3, NM_020185.6, NR_104473.3, NR_104474.3, NR_104475.3
- RefSeq protein
- NP_001273484.1, NP_064570.1, XP_011513059.1, XP_016866551.1, XP_054211915.1
Enables non-membrane spanning protein tyrosine phosphatase activity and protein tyrosine kinase binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; negative regulation of focal adhesion assembly; and negative regulation of non-membrane spanning protein tyrosine kinase activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in plasma membrane. Part of cytoplasm; filamentous actin; and leading edge of lamellipodium. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
negative regulation of transcription by RNA polymerase IInegative regulation of cell adhesionsignal transductiontransforming growth factor beta receptor signaling pathwaynegative regulation of cell migrationintracellular signal transductionpositive regulation of JNK cascadenegative regulation of T cell receptor signaling pathway
Molecular function
protein serine/threonine phosphatase activityprotein tyrosine phosphatase activityprotein tyrosine phosphatase activityprotein tyrosine phosphatase activitynon-membrane spanning protein tyrosine phosphatase activityprotein tyrosine/serine/threonine phosphatase activityprotein tyrosine kinase inhibitor activityprotein tyrosine kinase binding
via MyGene.info
Gene · Ensembl
dual specificity phosphatase 22
- Symbol
- DUSP22
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:291,630-369,379
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- PBB Protein DUSP22 image.jpg
Show 7 more facts
- HomoloGene ID
- 86039
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/56940
- genomic end
- 351355
- genomic start
- 291630
- chromosome
- human chromosome 6
- cytogenetic location
- 6p25.3
Sources (3)
via Wikidata · CC0