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ヒドラメチルノン

Structure via PubChem · Public domain (PubChem)

EntityQ413481· pop 12· linked from 213 articles

ヒドラメチルノン

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Also known as (1E,4E)-1,5-bis[4-(trifluoromethyl)phenyl]-1,4-pentadien-3-one (5,5-dimethyltetrahydro-2(1H)-pyrimidinylidene)hydrazone, Amdro, hydramethylnon

Hydramethylnon (AC 217,300) is an insecticide used primarily in the form of baits for cockroaches and ants. It works by inhibiting complex III in the mitochondrial inner membrane and leads to a halting of oxidative phosphorylation (IRAC class 20A). Some brands of hydramethylnon are Amdro, Blatex, Combat, Cyaforce, Cyclon, Faslane, Grant's, Impact, Matox, Maxforce, Pyramdron, Siege, Scuttle and Wipeout. Hydramethylnon is a slow-acting poison with delayed toxicity that needs to be eaten to be effective.

Chemical data

Formula
C25H24F6N4
Molecular weight
494.5 g/mol
IUPAC name
N-[[(1E,4E)-1,5-bis[4-(trifluoromethyl)phenyl]penta-1,4-dien-3-ylidene]amino]-5,5-dimethyl-4,6-dihydro-1H-pyrimidin-2-amine
SMILES
CC1(CN=C(NC1)NN=C(/C=C/C2=CC=C(C=C2)C(F)(F)F)/C=C/C3=CC=C(C=C3)C(F)(F)F)C
InChIKey
IQVNEKKDSLOHHK-FNCQTZNRSA-N
XLogP
6.4
Polar surface area
48.8 Ų
H-bond donors
2
H-bond acceptors
8
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
494.190516
Show 4 more facts
chemical formula
C₂₅H₂₄F₆N₄
canonical SMILES
CC1(CNC(=NC1)NN=C(C=CC2=CC=C(C=C2)C(F)(F)F)C=CC3=CC=C(C=C3)C(F)(F)F)C
isomeric SMILES
CC1(CN=C(NC1)NN=C(/C=C/C2=CC=C(C=C2)C(F)(F)F)/C=C/C3=CC=C(C=C3)C(F)(F)F)C
Commons category
Hydramethylnon
Sources (3)

via Wikidata · CC0

Article · 日本語

ヒドラメチルノン(英 Hydramethylnon)は有機フッ素化合物の一種。やなどの毒餌式殺虫剤に配合され、ゴキブリやアリの駆除に使用される。昆虫のミトコンドリアにおける電子伝達系に作用し、エネルギー代謝を阻害することで効果が生じる。同剤を直接摂取した虫だけでなく、同剤を摂取した虫の糞や死骸を食べた虫に対しても殺虫効果が現れることから、「一度で二度効く」のキャッチコピーで宣伝されている(ドミノ効果)。

Abstract from DBpedia / Wikipedia · CC BY-SA