آنزیم ای کو آر ۱
Sign in to saveAlso known as Restriction endonuclease, type II, EcoRI, Restrct_endonuc_II_EcoRI, IPR004221
EcoRI (pronounced "eco R one") is a type II restriction enzyme isolated from Escherichia coli. It cleaves DNA double helices into fragments at specific sites, and is also a part of the restriction modification system. The enzyme's name originates from the species from which it was isolated: "E" denotes generic name (Escherichia), "co" denotes species name (coli), "R" represents the strain (RY13), and the "I" denotes that it was the first enzyme isolated from this strain.
Key facts
- Protein family.Symbol
- EcoRI
- Protein family.Name
- EcoRI
- Protein family.image
- Ecor1_2ckq.png
- Protein family.caption
- EcoRI crystal structure. Dimer bound to DNA (PDB
- Protein family.Pfam
- PF02963
- Protein family.InterPro
- IPR004221
- Protein family.SCOP
- 1na6
- Protein family.CDD
- 79lll
via Wikipedia infobox
Research
8,897 papers- How the EcoRI endonuclease recognizes and cleaves DNA.BioEssays : news and reviews in molecular, cellular and developmental biology · 1992
- In-silicon studies on hydration in EcoRI-cognate DNA complex.Biophysical chemistry · 2023
- Effect of osmolytes on the EcoRI endonuclease: Insights into hydration and protein dynamics from molecular dynamics simulations.Computational biology and chemistry · 2023
- HindIII/EcoRI polymorphism in the GAA gene.Nucleic acids research · 1990
- Substrate recognition by the EcoRI endonuclease.Proteins · 1990
via PubMed
Wikidata facts
Show 5 more facts
- recognition sequence
- GAATTC
- cutting site of restriction enzyme
- G^AATTC
- produces cohesive end
- ^AATT
- natural product of taxon
- Escherichia coli
- Commons category
- Restriction endonuclease EcoRI
Sources (9)
via Wikidata · CC0