Also known as HEED, WAIT1, embryonic ectoderm development, COGIS
protein-coding gene in the species Homo sapiens
Gene data
EED- Name
- embryonic ectoderm development
- Type
- protein-coding
- Position
- 86,201,212–86,279,811 (+)
- Aliases
- COGIS, HEED, WAIT1
- Ensembl
- ENSG00000074266
- RefSeq RNA
- NM_001308007.2, NM_001330334.2, NM_001440586.1, NM_001440587.1, NM_001440588.1
- RefSeq protein
- NP_001294936.1, NP_001317263.1, NP_001427515.1, NP_001427516.1, NP_001427517.1
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
embryonic ectoderm development
- Symbol
- EED
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:86,201,212-86,279,811
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI