Structure via PubChem · Public domain (PubChem)
elacestrant
Sign in to saveElacestrant, sold under the brand name Orserdu, is a selective estrogen receptor degrader (SERD) used in the treatment of breast cancer. It is taken by mouth.
Chemical data
- Formula
- C30H38N2O2
- Molecular weight
- 458.6 g/mol
- IUPAC name
- (6R)-6-[2-[ethyl-[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
- SMILES
- CCNCCC1=CC=C(C=C1)CN(CC)C2=C(C=CC(=C2)OC)[C@@H]3CCC4=C(C3)C=CC(=C4)O
- InChIKey
- SIFNOOUKXBRGGB-AREMUKBSSA-N
- XLogP
- 6.3
- Polar surface area
- 44.7 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 458.293
Show 3 more facts
- canonical SMILES
- CCNCCC1=CC=C(C=C1)CN(CC)C2=C(C=CC(=C2)OC)C3CCC4=C(C3)C=CC(=C4)O
- chemical formula
- C₃₀H₃₈N₂O₂
- isomeric SMILES
- CCNCCC1=CC=C(C=C1)CN(CC)C2=C(C=CC(=C2)OC)[C@@H]3CCC4=C(C3)C=CC(=C4)O
Sources (1)
via Wikidata · CC0
~6 min read
Encyclopedic overview
7 sectionsContents
- Medical uses
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- History
- Research
- References
{{Infobox drug | image = Elacestrant.svg | image_class = skin-invert-image | width = 225px
| pronounce = | tradename = Orserdu | Drugs.com = | MedlinePlus = | licence_CA = | licence_EU = | DailyMedID = Elacestrant | licence_US = | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth | class = | ATCvet = | ATC_prefix = L02 | ATC_suffix = BA04 | ATC_supplemental =
Excerpted from Wikipedia’s “elacestrant” article, available under the CC BY-SA 4.0 licence.