equilin
Sign in to saveAlso known as 7-Dehydroestrone, 1,3,5,7-Estratetraen-3-ol-17-one, Dihydroequilenin
Equilin is a naturally occurring estrogen sex hormone found in horses as well as a medication. It is one of the estrogens present in the estrogen combination drug preparations known as conjugated estrogens (CEEs; e.g. Premarin) and esterified estrogens (EEs; e.g. Estratab, Menest). CEEs is the most commonly used form of estrogen medications in hormone replacement therapy (HRT) for menopausal symptoms in the United States. Estrone sulfate is the major estrogen in CEEs (about 50%) while equilin sulfate is the second major estrogen in the formulation, present as about 25% of the total.
Research
258 papers- Equilin.Acta crystallographica. Section C, Crystal structure communications · 1999
- Equilin in conjugated equine estrogen increases monocyte-endothelial adhesion via NF-κB signaling.PloS one · 2019
- Equilin displays similar endothelium-independent vasodilator potential to 17β-estradiol regardless of lower potential to inhibit calcium entry.Steroids · 2019
- Metabolism of equilin sulfate in the dog.The Journal of steroid biochemistry and molecular biology · 1995
- Effects of 17β-estradiol and equilin on atherosclerosis development in female Apoe(shl) mice.Scientific reports · 2025
via PubMed
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Encyclopedic overview
5 sectionsContents
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- References
Equilin is a naturally occurring estrogen sex hormone found in horses as well as a medication. It is one of the estrogens present in the estrogen combination drug preparations known as conjugated estrogens (CEEs; e.g. Premarin) and esterified estrogens (EEs; e.g. Estratab, Menest). CEEs is the most commonly used form of estrogen medications in hormone replacement therapy (HRT) for menopausal symptoms in the United States. Estrone sulfate is the major estrogen in CEEs (about 50%) while equilin sulfate is the second major estrogen in the formulation, present as about 25% of the total.
==Pharmacology==
Excerpted from Wikipedia’s “equilin” article, available under the CC BY-SA 4.0 licence.