FANCI

Name

FA complementation group I

Type

protein-coding

Position

89,243,854–89,318,091 (+)

Aliases

KIAA1794

Ensembl

ENSG00000140525

RefSeq RNA

NM_001113378.2, NM_001376910.1, NM_001376911.1, NM_018193.3, XM_011521756.3

RefSeq protein

NP_001106849.1, NP_001363839.1, NP_001363840.1, NP_060663.2, XP_011520058.1

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

FA complementation group I

Symbol

FANCI

Biotype

Protein coding

Organism

Homo sapiens

Location

15:89,243,854-89,318,091

Strand

Forward (+)

Assembly

GRCh38