FEZ1
Sign in to saveAlso known as UNC-76, fasciculation and elongation protein zeta 1
Fasciculation and elongation protein zeta-1 is a protein that in humans is encoded by the FEZ1 gene.
Gene data
FEZ1- Name
- fasciculation and elongation protein zeta 1
- Type
- protein-coding
- Aliases
- UNC-76
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
fasciculation and elongation protein zeta 1
- Symbol
- FEZ1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:125,442,881-125,592,578
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 21063
- exact match
- identifiers.org/ncbigene/9638
- genomic end
- 125592568
- genomic start
- 125442881
- cytogenetic location
- 11q24.2
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Fasciculation and elongation protein zeta-1 is a protein that in humans is encoded by the FEZ1 gene.
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.