Forkhead-Box-Protein E1
Sign in to saveAlso known as forkhead box protein E2, forkhead box protein E1, forkhead-related protein FKHL15, HFKL5, thyroid transcription factor 2, HFKH4, TTF-2, forkhead, drosophila, homolog-like 15
Protein in Homo sapiens
Protein · UniProt
Forkhead box protein E1
- Gene
- FOXE1
- Organism
- Homo sapiens (Human)
- Length
- 373 aa
- Molecular mass
- 38,076 Da
- Evidence
- 1: Evidence at protein level
Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression
Swiss-Prot (reviewed) · via UniProt
Wikidata facts
- Instance of
- protein
Show 2 more facts
- cell component
- nucleus
- found in taxon
- Homo sapiens
Sources (3)
via Wikidata · CC0
Article · Deutsch
Das Forkhead-Box-Protein E1 (FOXE1), auch Thyroidaler Transkriptionsfaktor 2 (TTF-2) genannt, ist ein Protein, das als Transkriptionsfaktor unter anderem die Transkription von bestimmten Genen in der Schilddrüse kontrolliert. Das für das FOXE1-Protein codierende Gen FOXE1 zählt zur Familie der Forkhead-Box-Gene. FOXE1 ist nicht nur im Menschen, sondern auch in einer Vielzahl von Tierarten nachgewiesen worden.
Abstract from DBpedia / Wikipedia · CC BY-SA