ZPR1
Sign in to saveAlso known as ZNF259, ZPR1 zinc finger, GKAF
Zinc finger protein ZPR1 is a protein that in humans is encoded by the ZNF259 gene.
Gene data
ZPR1- Name
- ZPR1 zinc finger
- Type
- protein-coding
- Position
- 116,773,799–116,788,477 (−)
- Aliases
- GKAF, ZNF259
- Ensembl
- ENSG00000109917
- RefSeq RNA
- NM_001317086.2, NM_003904.5, XM_047427804.1, XM_054370365.1
- RefSeq protein
- NP_001304015.1, NP_003895.1, XP_047283760.1, XP_054226340.1
The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
ZPR1 zinc finger
- Symbol
- ZPR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:116,773,799-116,788,477
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 2900
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8882
- genomic end
- 116788039
- genomic start
- 116648436
- chromosome
- human chromosome 11
- cytogenetic location
- 11q23.3
- expressed in
- smooth muscle tissue
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Zinc finger protein ZPR1 is a protein that in humans is encoded by the ZNF259 gene.
== References ==
Excerpted from Wikipedia’s “ZPR1” article, available under the CC BY-SA 4.0 licence.