GDI2
Sign in to saveAlso known as HEL-S-46e, RABGDIB, GDP dissociation inhibitor 2
Rab GDP dissociation inhibitor beta is a protein that in humans is encoded by the GDI2 gene.
Gene data
GDI2- Name
- GDP dissociation inhibitor 2
- Type
- protein-coding
- Aliases
- HEL-S-46e, RABGDIB
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
GDP dissociation inhibitor 2
- Symbol
- GDI2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:5,763,583-5,842,132
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 37488
- exact match
- identifiers.org/ncbigene/2665
- genomic end
- 5884095
- genomic start
- 5807186
- cytogenetic location
- 10p15.1
Sources (4)
via Wikidata · CC0
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Article
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- Further reading
Rab GDP dissociation inhibitor beta is a protein that in humans is encoded by the GDI2 gene.
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.