genomic imprinting
Sign in to saveAlso known as genetic imprinting, GO:0071514, DNA imprinting
phenomenon that causes genes to be expressed in a parent-of-origin-specific manner
Research
9,185 papers- Genomic Imprinting and Physiological Processes in Mammals.Cell · 2019
- Genomic imprinting in plants-revisiting existing models.Genes & development · 2020
- Genomic Imprinting and Random Monoallelic Expression.Biochemistry. Biokhimiia · 2024
- Genomic imprinting.Current biology : CB · 2004
- Genomic imprinting regulates establishment and release of seed dormancy.Current opinion in plant biology · 2022
via PubMed
~24 min read
Encyclopedic overview
Genomic imprinting is an epigenetic phenomenon that causes genes to be expressed or not, depending on whether they are inherited from the female or male parent. Genes can also be partially imprinted. Partial imprinting occurs when alleles from both parents are differently expressed rather than complete expression and complete suppression of one parent's allele. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. As of 2019, 260 imprinted genes have been reported in mice and 228 in humans.
Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. It is an epigenetic process that involves DNA methylation and histone methylation without altering the genetic sequence. These epigenetic marks are established ("imprinted") in the germline (sperm or egg cells) of the parents and are maintained through mitotic cell divisions in the somatic cells of an organism.
Excerpted from Wikipedia’s “genomic imprinting” article, available under the CC BY-SA 4.0 licence.