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gigantine

Structure via PubChem · Public domain (PubChem)

EntityQ5560213· pop 7· linked from 1,092 articles

Gigantine is a tetrahydroisoquinoline alkaloid found in Carnegiea gigantea and other related cactus species. It was first discovered along with macromerine in 1967. Gigantine is found in significant quantities in many mescaline-containing cactus species, but it is unclear whether it contributes to their psychoactive effects. The compound has been suspected to be hallucinogenic based on animal studies in cats and monkeys, but has not been evaluated in humans.

Chemical data

Formula
C13H19NO3
Molecular weight
237.29 g/mol
IUPAC name
(1S)-6,7-dimethoxy-1,2-dimethyl-3,4-dihydro-1H-isoquinolin-5-ol
SMILES
C[C@H]1C2=CC(=C(C(=C2CCN1C)O)OC)OC
InChIKey
HRJQUAXWKYISJC-QMMMGPOBSA-N
XLogP
1.8
Polar surface area
41.9 Ų
H-bond donors
1
H-bond acceptors
4
Formal charge
0

via PubChem

Wikidata facts

Mass
237.136493
Show 4 more facts
chemical formula
C₁₃H₁₉NO₃
isomeric SMILES
C[C@H]1C2=CC(=C(C(=C2CCN1C)O)OC)OC
canonical SMILES
CC1C2=CC(=C(C(=C2CCN1C)O)OC)OC
found in taxon
Carnegiea gigantea
Sources (2)

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Encyclopedic overview

3 sections
Contents
  • See also
  • References
  • External links

Gigantine is a tetrahydroisoquinoline alkaloid found in Carnegiea gigantea and other related cactus species. It was first discovered along with macromerine in 1967. Gigantine is found in significant quantities in many mescaline-containing cactus species, but it is unclear whether it contributes to their psychoactive effects. The compound has been suspected to be hallucinogenic based on animal studies in cats and monkeys, but has not been evaluated in humans.

==See also== Substituted tetrahydroisoquinoline

Excerpted from Wikipedia’s “gigantine” article, available under the CC BY-SA 4.0 licence.

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