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m-tyramine

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EntityQ6553277· pop 8· linked from 1,194 articles

m-tyramine

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Also known as 3-(2-Aminoethyl)phenol, Meta-tyramine, 3-Hydroxyphenethylamine, 3-Tyramine, 3-Hydroxyphenylethylamine, Metatyramine, 2-(3-Hydroxyphenyl)ethylamine, M-Hydroxyphenethylamine

'''meta-Tyramine, also known as m-tyramine and 3-tyramine, as well as 3-hydroxyphenethylamine', is an endogenous trace amine neuromodulator and a structural analog of phenethylamine. It is a positional isomer of para''-tyramine, and similarly to it, has effects on the adrenergic and dopaminergic systems.

Chemical data

Formula
C8H11NO
Molecular weight
137.18 g/mol
IUPAC name
3-(2-aminoethyl)phenol
SMILES
C1=CC(=CC(=C1)O)CCN
InChIKey
GHFGJTVYMNRGBY-UHFFFAOYSA-N
XLogP
0.9
Polar surface area
46.3 Ų
H-bond donors
2
H-bond acceptors
2
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
137.084
Show 3 more facts
canonical SMILES
C1=CC(=CC(=C1)O)CCN
Commons category
Meta-Tyramine
chemical formula
C₈H₁₁NO
Sources (2)

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Encyclopedic overview

2 sections
Contents
  • See also
  • References

'''meta-Tyramine, also known as m-tyramine and 3-tyramine, as well as 3-hydroxyphenethylamine', is an endogenous trace amine neuromodulator and a structural analog of phenethylamine. It is a positional isomer of para-tyramine, and similarly to it, has effects on the adrenergic and dopaminergic systems.

meta-Tyramine is produced in humans via aromatic amino acid decarboxylase-mediated metabolism of meta-tyrosine. meta-Tyramine can be metabolized into dopamine via peripheral or brain CYP2D6 enzymes in humans.

Excerpted from Wikipedia’s “m-tyramine” article, available under the CC BY-SA 4.0 licence.

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