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HOT-7

Structure via PubChem · Public domain (PubChem)

EntityQ5635482· pop 6· linked from 661 articles

Also known as 2,5-dimethoxy-4-(β-propylthio)-N-hydroxyphenethylamine

HOT-7, also known as '4-propylthio-2,5-dimethoxy-N-hydroxyphenethylamine or as N-hydroxy-2C-T-7', is a psychedelic drug of the phenethylamine, 2C, and HOT-x families. It is the N-hydroxy derivative of 2C-T-7. The drug is taken orally.

Chemical data

Formula
C13H21NO3S
Molecular weight
271.38 g/mol
IUPAC name
N-[2-(2,5-dimethoxy-4-propylsulfanylphenyl)ethyl]hydroxylamine
SMILES
CCCSC1=C(C=C(C(=C1)OC)CCNO)OC
InChIKey
ASTNLROMDNGJLS-UHFFFAOYSA-N
XLogP
2.7
Polar surface area
76 Ų
H-bond donors
2
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
271.124214532
Show 2 more facts
canonical SMILES
COc1cc(SCCC)c(cc1CCNO)OC
chemical formula
C₁₃H₂₁NO₃S
Sources (2)

via Wikidata · CC0

~2 min read

Encyclopedic overview

13 sections
Contents
  • Use and effects
  • Interactions
  • Chemistry
  • Synthesis
  • Analogues
  • History
  • Society and culture
  • Legal status
  • Canada
  • United Kingdom
  • See also
  • References
  • External links

HOT-7, also known as '4-propylthio-2,5-dimethoxy-N-hydroxyphenethylamine or as N-hydroxy-2C-T-7', is a psychedelic drug of the phenethylamine, 2C, and HOT-x families. It is the N-hydroxy derivative of 2C-T-7. The drug is taken orally.

==Use and effects== In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists HOT-7's dose range as 15 to 20mg orally and its duration as 6 to 8hours. The drug's onset and peak of effects were not described. HOT-7's properties are similar to those of 2C-T-7, which has a dose of 10 to 30mg orally and a duration of 8 to 15hours, although HOT-7 may have a somewhat shorter duration. HOT-7 may act as a prodrug of 2C-T-7.

Excerpted from Wikipedia’s “HOT-7” article, available under the CC BY-SA 4.0 licence.

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