The globins are a superfamily of heme-containing globular proteins, involved in binding and/or transporting oxygen. These proteins all incorporate the globin fold, a series of eight alpha helical segments. Two prominent members include myoglobin and hemoglobin. Both of these proteins reversibly bind oxygen via a heme prosthetic group. They are widely distributed in many organisms.
Key facts
- Protein family.Symbol
- Protoglobin
- Protein family.Name
- Protoglobin (family S)
- Protein family.image
- PDB 1s56 EBI.jpg
- Protein family.caption
- crystal structure of "truncated" hemoglobin n (hbn) from mycobacterium tuberculosis, soaked with xe atoms
- Protein family.Pfam
- PF11563
- Protein family.Pfam_clan
- CL0090
- Protein family.ECOD
- 106.1.1
- Protein family.InterPro
- IPR012102
- Protein family.PROSITE
- PDOC00933
- Protein family.SCOP
- 1dlw
- Protein family.CDD
- cd01068
via Wikipedia infobox
Research
176,405 papers- Globin phylogeny, evolution and function, the newest update.Proteins · 2024
- Mechanisms of Globin Gene Regulation in Mammals.Annual review of genetics · 2025
- Globin genes on the move.Journal of biology · 2008
- Segregation of α- and β-Globin Gene Cluster in Vertebrate Evolution: Chance or Necessity?Biochemistry. Biokhimiia · 2022
- Lessons from the post-genomic era: Globin diversity beyond oxygen binding and transport.Redox biology · 2020
via PubMed
Wikidata facts
- Subclass of
- heme protein
- Image
- PDB 1hba EBI.jpg
Show 1 more fact
- Commons category
- Globins
Sources (2)
via Wikidata · CC0
Article · 中文
珠蛋白（英語：Globin）是含有血红素的球状蛋白质的超家族，涉及结合和/或运输氧气。这些蛋白质都包含珠蛋白折叠，有八个α螺旋片段的一种系列。两个突出的成员包括肌红蛋白和血红蛋白。这两种蛋白质都可以通过血基質假体组可逆地结合氧。它们广泛分布在许多生物体中。
Abstract from DBpedia / Wikipedia · CC BY-SA