hematin
Sign in to saveAlso known as Fe(ppIX)(OH), [Fe(ppIX)(OH)], hydroxo[3,7,12,17-tetramethyl-8,13-divinylporphyrin-2,18-dipropanoato(2-)]iron(III), phenodin, hydroxyhemin, ferriprotoporphyrin basic, ferriprotoporphyrin IX hydroxide, ferriporphyrin hydroxide
Haematin (also known as hematin, ferriheme, hematosin, hydroxyhemin, oxyheme, phenodin, or oxyhemochromogen) is a dark bluish or brownish pigment containing iron in the ferric state, obtained by the oxidation of haem.
Wikidata facts
- Mass
- 633.180032656
Show 2 more facts
- chemical formula
- C₃₄H₃₃FeN₄O₅
- canonical SMILES
- C=Cc1c(C)c2cc3nc(cc4nc(cc5[nH]c(cc1[n-]2)c(C)c5C=C)C(C)=C4CCC(=O)[O-])C(CCC(=O)[O-])=C3C.O.[Fe+3]
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Haematin (also known as hematin, ferriheme, hematosin, hydroxyhemin, oxyheme, phenodin, or oxyhemochromogen) is a dark bluish or brownish pigment containing iron in the ferric state, obtained by the oxidation of haem.
Haematin inhibits the synthesis of porphyrin (by repressing ALAS1 synthesis), and stimulates the synthesis of globin. For this reason, it is used in the treatment of porphyrias.