hemoglobin
Sign in to saveHemoglobin (haemoglobin, Hb or Hgb) is a protein containing iron that facilitates the transportation of oxygen in red blood cells. Almost all vertebrates contain hemoglobin, with the sole exception of the fish family Channichthyidae. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the other tissues of the body, where it releases the oxygen to enable aerobic respiration which powers an animal's metabolism. A healthy human has 12to 20grams of hemoglobin in every 100mL of blood. Hemoglobin is a metalloprotein, a chromoprotein, and a globulin.
AI overview
Hemoglobin is an iron-containing protein in red blood cells that transports oxygen from your lungs to the rest of your body, where it delivers that oxygen to power your cells. It's found in nearly all vertebrates and is essential for the aerobic respiration that keeps your metabolism running.
AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Heteropolypeptide.heteropolymer
- Hemoglobin
- Heteropolypeptide.polymer_type
- heterotetramer, (αβ)2
- Heteropolypeptide.protein_type
- metalloprotein, chromoprotein, globulin
- Heteropolypeptide.function
- oxygen-transport
- Heteropolypeptide.cofactors
- heme (4)
- Heteropolypeptide.image
- 1GZX Haemoglobin.png
- Heteropolypeptide.image_source
- Structure of human hemoglobin. α and β globin subunits are in red and blue, respectively, and the iron-containing heme groups in green. From
- Heteropolypeptide.SubunitCount
- 3
- Heteropolypeptide.subunit1
- Hb-α1
- Heteropolypeptide.gene1
- HBA1
- Heteropolypeptide.locus1
- Chr. 16 p13.3
- Heteropolypeptide.subunit2
Article
31 sectionsContents
- Research history
- Genetics
- Evolution
- Evolution of vertebrate hemoglobin
- Fish
- Birds
- Mammals
- Synthesis
- Structure of heme
- Oxygen saturation
- Oxyhemoglobin
- Deoxygenated hemoglobin
- Cooperativity
- Binding of ligands other than oxygen
- Competitive
- Allosteric
- Types of hemoglobin in humans
- Degradation in vertebrate animals
- Diseases related to hemoglobin
- Diagnostic uses
- Athletic tracking and self-tracking uses
- Analogues in non-vertebrate organisms
- Other oxygen-binding proteins
- Presence in nonerythroid cells
- In history and art
- See also
- References
- Notes
- Sources
- Further reading
- External links
Hemoglobin (haemoglobin, Hb or Hgb) is a protein containing iron that facilitates the transportation of oxygen in red blood cells. Almost all vertebrates contain hemoglobin, with the sole exception of the fish family Channichthyidae. Hemoglobin in the blood carries oxygen from the respiratory organs (lungs or gills) to the other tissues of the body, where it releases the oxygen to enable aerobic respiration which powers an animal's metabolism. A healthy human has 12to 20grams of hemoglobin in every 100mL of blood. Hemoglobin is a metalloprotein, a chromoprotein, and a globulin.
In mammals, hemoglobin makes up about 96% of a red blood cell's dry weight (excluding water), and around 35% of the total weight (including water). Hemoglobin has an oxygen-binding capacity of 1.34mL of O2 per gram, which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood plasma alone. The mammalian hemoglobin molecule can bind and transport up to four oxygen molecules.