GOPC

Also known as CAL, FIG, GOPC1, PIST, dJ94G16.2, golgi-associated PDZ and coiled-coil motif containing, golgi associated PDZ and coiled-coil motif containing

Golgi-associated PDZ and coiled-coil motif-containing protein is a protein that in humans is encoded by the GOPC gene.

Gene data

GOPC

Name: golgi associated PDZ and coiled-coil motif containing
Type: protein-coding
Position: 117,560,269–117,602,553 (−)
Aliases: CAL, FIG, GOPC1, PIST, dJ94G16.2
Ensembl: ENSG00000047932
RefSeq RNA: NM_001017408.3, NM_020399.4, XM_054355977.1
RefSeq protein: NP_001017408.1, NP_065132.1, XP_054211952.1

This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].

Pathways

Signal Transduction Signaling by Rho GTPases RHO GTPase Effectors RHO GTPases regulate CFTR trafficking RHO GTPase cycle RHOQ GTPase cycle Signaling by Rho GTPases, Miro GTPases and RHOBTB3

via MyGene.info

Gene · Ensembl

golgi associated PDZ and coiled-coil motif containing

Symbol: GOPC
Biotype: Protein coding
Organism: Homo sapiens
Location: 6:117,560,269-117,602,553
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein GOPC PDB 2dc2.png

Show 8 more facts

found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/57120
HomoloGene ID: 10695
genomic end: 117923691
genomic start: 117639374
chromosome: human chromosome 6
cytogenetic location: 6q22.1
expressed in: Achilles tendon

Sources (4)

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Encyclopedic overview

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Contents

Interactions
References
Further reading

Golgi-associated PDZ and coiled-coil motif-containing protein is a protein that in humans is encoded by the GOPC gene.

PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM]

Excerpted from Wikipedia’s “GOPC” article, available under the CC BY-SA 4.0 licence.