RHOQ

Name

ras homolog family member Q

Type

protein-coding

Position

46,541,806–46,602,046 (+)

Aliases

ARHQ, HEL-S-42, RASL7A, TC10, TC10A

Ensembl

ENSG00000119729

RefSeq RNA

NM_012249.4, XM_005264229.3, XM_011532726.3, XM_054341206.1, XM_054341207.1

RefSeq protein

NP_036381.2, XP_005264286.1, XP_011531028.1, XP_054197181.1, XP_054197182.1

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011].

via MyGene.info

Gene · Ensembl

ras homolog family member Q

Symbol

RHOQ

Biotype

Protein coding

Organism

Homo sapiens

Location

2:46,541,806-46,602,046

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein RHOQ PDB 2atx.png

via Wikidata · CC0