Gustducin [plasma membrane]
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Gustducin is a G protein associated with taste and the gustatory system, found in some taste receptor cells. Research on the discovery and isolation of gustducin is recent. It is known to play a large role in the transduction of bitter, sweet and umami stimuli. Its pathways (especially for detecting bitter stimuli) are many and diverse.
Wikidata facts
- Instance of
- protein complex
Show 2 more facts
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/reactome:R-HSA-400532
Sources (1)
via Wikidata · CC0
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Encyclopedic overview
13 sectionsContents
- Discovery
- Comparisons with transducin
- Location
- Evolution of the gustducin-mediated signaling model
- Second messengers IP<sub>3</sub> and cAMP
- Bitter transduction
- Sweet transduction
- Evolution of bitter taste receptors
- Gustducin in the stomach
- See also
- References
- Further reading
- External links
Gustducin is a G protein associated with taste and the gustatory system, found in some taste receptor cells. Research on the discovery and isolation of gustducin is recent. It is known to play a large role in the transduction of bitter, sweet and umami stimuli. Its pathways (especially for detecting bitter stimuli) are many and diverse.
An intriguing feature of gustducin is its similarity to transducin. These two G proteins have been shown to be structurally and functionally similar, leading researchers to believe that the sense of taste evolved in a similar fashion to the sense of sight.
Excerpted from Wikipedia’s “Gustducin [plasma membrane]” article, available under the CC BY-SA 4.0 licence.