dynein
Sign in to savethumbnail|right|Cytoplasmic dynein on a microtubule Dyneins are a family of cytoskeletal motor proteins (though they are actually protein complexes) that move along microfilaments in cells. They convert the chemical energy stored in ATP to mechanical work. Dynein transports various cellular cargos, provides forces and displacements important in mitosis, and drives the beat of eukaryotic cilia and flagella. All of these functions rely on dynein's ability to move towards the minus-end of the microtubules, known as retrograde transport; thus, they are called "minus-end directed motors". In contra
Key facts
- Protein family.Symbol
- Robl1, Robl2
- Protein family.Name
- Roadblock
- Protein family.Pfam
- PF03259
- Protein family.InterPro
- IPR016561
- Protein family.caption
- Structure of Roadblock/LC7 protein - RCSB PDB 1y4o
- Protein family.Pfam_clan
- CL0023
- Protein family.PDB
- http://www.rcsb.org/pdb/explore/explore.do?structureId=4w7g
- Protein family.image
- Roadblock protein RCSB PDB 1y4o screenshot.png
- Protein family.PROSITE
- PDOC00953
- Protein family.SCOP
- 1y4o
via Wikipedia infobox
Article
13 sectionsContents
- Classification
- Function
- Mitotic spindle positioning
- Viral replication
- Structure
- Cytoplasmic dynein
- Axonemal dynein
- History
- Chromosome segregation during meiosis
- See also
- References
- Further reading
- External links
thumbnail|right|Cytoplasmic dynein on a microtubule Dyneins are a family of cytoskeletal motor proteins (though they are actually protein complexes) that move along microfilaments in cells. They convert the chemical energy stored in ATP to mechanical work. Dynein transports various cellular cargos, provides forces and displacements important in mitosis, and drives the beat of eukaryotic cilia and flagella. All of these functions rely on dynein's ability to move towards the minus-end of the microtubules, known as retrograde transport; thus, they are called "minus-end directed motors". In contrast, most kinesin motor proteins move toward the microtubules' plus-end, in what is called anterograde transport.
==Classification==