Also known as HIS, HSTD, histidine ammonia-lyase, Histidine ammonia-lyase
gen de la especie Homo sapiens
Gene data
HAL- Name
- histidine ammonia-lyase
- Type
- protein-coding
- Position
- 95,972,662–95,996,365 (−)
- Aliases
- HIS, HSTD
- Ensembl
- ENSG00000084110
- RefSeq RNA
- NM_001258333.2, NM_001258334.2, NM_002108.4, XM_011538249.3, XM_017019246.1
- RefSeq protein
- NP_001245262.1, NP_001245263.1, NP_002099.1, XP_011536551.1, XP_016874735.1
Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
histidine ammonia-lyase
- Symbol
- HAL
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:95,972,662-95,996,365
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 68229
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3034
- genomic end
- 96390143
- genomic start
- 96366440
- chromosome
- human chromosome 12
- cytogenetic location
- 12q23.1
- genetic association
- histidinemia
- Commons category
- Histidine ammonia-lyase (HAL)
Sources (4)
via Wikidata · CC0