hepatoblastoma
Hepatoblastoma is a malignant liver cancer occurring in infants and children and composed of tissue resembling fetal liver cells, mature liver cells, or bile duct cells. They usually present with an abdominal mass. The disease is most commonly diagnosed during a child's first three years of life. Alpha-fetoprotein (AFP) levels are commonly elevated, but when AFP is not elevated at diagnosis the prognosis is poor.
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- Hepatoblastoma
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- Micrograph of a hepatoblastoma. H&E stain.
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Article
6 sectionsContents
- Signs and symptoms
- Pathophysiology
- Diagnosis
- Treatment
- References
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Hepatoblastoma is a malignant liver cancer occurring in infants and children and composed of tissue resembling fetal liver cells, mature liver cells, or bile duct cells. They usually present with an abdominal mass. The disease is most commonly diagnosed during a child's first three years of life. Alpha-fetoprotein (AFP) levels are commonly elevated, but when AFP is not elevated at diagnosis the prognosis is poor.
==Signs and symptoms== Patients are usually asymptomatic at diagnosis. As a result, disease is often advanced at diagnosis.