fibromatosis
Sign in to saveThe term fibromatosis refers to a group of soft tissue tumors which have certain characteristics in common, including absence of cytologic and clinical malignant features, a histology consistent with proliferation of well-differentiated fibroblasts, an infiltrative growth pattern, and aggressive clinical behavior with frequent local recurrence. It is classed by the World Health Organization as an intermediate soft tissue tumor related to the sarcoma family. Arthur Purdy Stout coined the term fibromatosis (in the name congenital generalized fibromatosis, describing myofibromatosis), in 1954.
Key facts
- Medical condition (new).name
- Fibromatosis
- Medical condition (new).image
- File:Desmoid-type fibromatosis.gross pathology.jpg
- Medical condition (new).field
- oncology
via Wikipedia infobox
Health references
- ICD-10
- M72.9 — Fibroblastic disorder, unspecified
Clinical Trials
68 registered- RECRUITINGProject: Every Child for Younger Patients With CancerChildren's Oncology Group · NCT02402244
- PHASE2COMPLETEDPhase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare DiseasesNovartis Pharmaceuticals · NCT00154388
- PHASE1COMPLETEDStudy of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)Salubris Biotherapeutics Inc · NCT04210375
- PHASE1/PHASE2ACTIVE_NOT_RECRUITINGA Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid TumoursCancer Research UK · NCT05057013
- RECRUITINGProspective Clinical Trial on the Impact of Uterine Firomatosis on Pelvic Floor.Fondazione IRCCS Policlinico San Matteo di Pavia · NCT07180524
- UNKNOWNCryoablation for Advanced and Refractory Desmoid TumorsUniversity Hospital, Strasbourg, France · NCT06113094
Wikidata facts
- Instance of
- rare disease
- Image
- Desmoid-type fibromatosis.gross pathology.jpg
Show 3 more facts
- Commons category
- Fibromatosis
- health specialty
- rheumatology
- NCI Thesaurus ID
- C3042
Sources (3)
via Wikidata · CC0
~3 min read
Encyclopedic overview
9 sectionsContents
- Diagnosis
- Juvenile subtypes
- Adult subtypes
- Superficial
- Deep
- Treatment
- Terminology
- References
- External links
The term fibromatosis refers to a group of soft tissue tumors which have certain characteristics in common, including absence of cytologic and clinical malignant features, a histology consistent with proliferation of well-differentiated fibroblasts, an infiltrative growth pattern, and aggressive clinical behavior with frequent local recurrence. It is classed by the World Health Organization as an intermediate soft tissue tumor related to the sarcoma family. Arthur Purdy Stout coined the term fibromatosis (in the name congenital generalized fibromatosis, describing myofibromatosis), in 1954.
==Diagnosis== ===Juvenile subtypes=== Subtypes of juvenile fibromatosis include: Infantile myofibromatosis: solitary tumors commonly occurring in the head and neck regions; multiple tumors occurring in the skin, subcutaneous tissue, muscles, and/or less commonly bones; or, rarely, tumors occurring in an internal organ(s). Aponeurotic fibroma Infantile digital fibromatosis Aggressive infantile fibromatosis Fibromatosis colli: benign sternocleidomastoid muscle tumor developing in infants within 8 weeks (average: 24 days) of delivery. It generally does not require resection and responds well to physiotherapy. Dermatofibrosis lenticularis (Buschke–Ollendorff syndrome) Fibromatosis hyalinica multiplex (juvenile hyaline fibromatosis) Lipofibromatosis
Excerpted from Wikipedia’s “fibromatosis” article, available under the CC BY-SA 4.0 licence.