hepatocyte
Sign in to saveAlso known as hepatocytes
A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver's mass. These cells are involved in: Protein synthesis Protein storage Transformation of carbohydrates Synthesis of cholesterol, bile salts and phospholipids Detoxification, modification, and excretion of exogenous and endogenous substances Initiation of formation and secretion of bile
Key facts
- Cell.Name
- Hepatocyte
- Cell.Image
- Sinusoid.jpeg
- Cell.Caption
- Hepatocyte and sinusoid (venule) in a section of rat liver, scanning electron micrograph
- Cell.Image2
- Human liver.jpg
- Cell.Caption2
- Human liver stained with hematoxylin and eosin showing hepatocytes organized into plates and lobules
- Cell.Location
- Liver
via Wikipedia infobox
Research
162,101 papers- Hepatocyte HSPA12A inhibits macrophage chemotaxis and activation to attenuate liver ischemia/reperfusion injury via suppressing glycolysis-mediated HMGB1 lactylation and secretion of hepatocytes.Theranostics · 2023
- Macrophages harness hepatocyte glutamate to boost liver regeneration.Nature · 2025
- CD1d protects against hepatocyte apoptosis in non-alcoholic steatohepatitis.Journal of hepatology · 2024
- TREM2 sustains macrophage-hepatocyte metabolic coordination in nonalcoholic fatty liver disease and sepsis.The Journal of clinical investigation · 2021
- Hepatocyte organoids and cell transplantation: What the future holds.Experimental & molecular medicine · 2021
via PubMed
Wikidata facts
- Image
- Human liver.jpg
Show 2 more facts
- Commons category
- Hepatocytes
- native label
- Hypocrita deforma
via Wikidata · CC0
~8 min read
Article
14 sectionsContents
- Structure
- Microanatomy
- Function
- Protein synthesis
- Carbohydrate metabolism
- Lipid metabolism
- Detoxification
- Aging
- Society and culture
- Use in research
- Additional images
- See also
- References
- External links
A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver's mass. These cells are involved in: Protein synthesis Protein storage Transformation of carbohydrates Synthesis of cholesterol, bile salts and phospholipids Detoxification, modification, and excretion of exogenous and endogenous substances Initiation of formation and secretion of bile
==Structure== The typical hepatocyte is cubical with sides of 20–30 μm, (in comparison, a human hair has a diameter of 17 to 180 μm). The typical volume of a hepatocyte is 3.4 x 10−9 cm3.