File:Animal_mitochondrion_diagram_en.svg · Wikimedia Commons · See Wikimedia Commons
mitochondrion
Sign in to saveAlso known as mitochondria, GO:0005739, maze bean, powerhouse of the cell
A mitochondrion () is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy. They were discovered by Albert von Kölliker in 1857 in the voluntary muscles of insects. The term mitochondrion, meaning a thread-like granule, was coined by Carl Benda in 1898. The mitochondrion is popularly nicknamed the "powerhouse of the cell", a phrase popularized by Philip Siekevitz in a 1957 Scientifi
A mitochondrion is a tiny structure found inside most animal, plant, and fungal cells that has a double membrane and converts oxygen and nutrients into a chemical energy molecule called ATP. This energy powers the cell's various functions, which is why mitochondria are often called the "powerhouse of the cell."
AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Microanatomy.Name
- Mitochondrion
- Microanatomy.Latin
- organella
- Microanatomy.Image
- Animal mitochondrion diagram en.svg
- Microanatomy.Caption
- Diagram of animal mitochondrion
- Microanatomy.PartOf
- Cell
via Wikipedia infobox
Research
288,999 papers- Of mitochondrion and COVID-19.ReviewJournal of enzyme inhibition and medicinal chemistry · 2021Alfarouk KO, Alhoufie STS, Hifny A et al.DOI: 10.1080/14756366.2021.1937144
- Mitochondrion-Targeted Type I Photodynamic Therapy for Agonist Independent cGAS-STING Activation.Advanced materials (Deerfield Beach, Fla.) · 2025Xu Y, An D, Zhang T et al.DOI: 10.1002/adma.202418894
- Mitochondrion: Main organelle in orchestrating cancer escape from chemotherapy.ReviewCancer reports (Hoboken, N.J.) · 2024Mostafavi S, Eskandari NDOI: 10.1002/cnr2.1942
- Mitochondrion-located peptides and their pleiotropic physiological functions.ReviewThe FEBS journal · 2022Zheng X, Xiang MDOI: 10.1111/febs.16532
- Was the Mitochondrion Necessary to Start Eukaryogenesis?ReviewTrends in microbiology · 2019Hampl V, Čepička I, Eliáš MDOI: 10.1016/j.tim.2018.10.005
- Microbe-mitochondrion crosstalk and health: An emerging paradigm.ReviewMitochondrion · 2018Bajpai P, Darra A, Agrawal ADOI: 10.1016/j.mito.2017.08.008
- THE MITOCHONDRION.ReviewScientific American · 1964GREEN DE
- Mitochondrial dysfunction and mitochondrion-targeted therapeutics in liver diseases.ReviewJournal of drug targeting · 2021Xiang L, Shao Y, Chen YDOI: 10.1080/1061186X.2021.1909051
via PubMed
Wikidata facts
- Image
- Mitochondria, mammalian lung - TEM.jpg
Show 5 more facts
- Commons gallery
- Mitochondrion
- Commons category
- Mitochondria
- exact match
- purl.obolibrary.org/obo/GO_0005739
- NCI Thesaurus ID
- C13258
- nickname
- maze bean
via Wikidata · CC0
~67 min read
Article
37 sectionsContents
- Structure
- Outer membrane
- Intermembrane space
- Inner membrane
- Cristae
- Matrix
- Function
- Energy conversion
- Pyruvate and the citric acid cycle
- O{{sub|2}} and NADH: energy-releasing reactions
- Heat production
- Mitochondrial fatty acid synthesis
- Uptake, storage and release of calcium ions
- Cellular proliferation regulation
- Programmed cell death and innate immunity
- Donation
- Additional functions
- Organization and distribution
- Mitochondria-associated ER membrane (MAM)
- Phospholipid transfer
- Calcium signaling
- Molecular basis for tethering
- Perspective
- <span class="anchor" id="origin_and_evolution_anchor">Origin and evolution</span>
- Mitochondrial genetics
- Human population genetic studies
- Alternative genetic code
- Replication and inheritance
- DNA repair
- Lack of mitochondrial DNA
- Dysfunction and disease
- Mitochondrial diseases
- Relationships to aging
- History
- See also
- References
- External links
A mitochondrion () is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy. They were discovered by Albert von Kölliker in 1857 in the voluntary muscles of insects. The term mitochondrion, meaning a thread-like granule, was coined by Carl Benda in 1898. The mitochondrion is popularly nicknamed the "powerhouse of the cell", a phrase popularized by Philip Siekevitz in a 1957 Scientific American article of the same name.
Some cells in some multicellular organisms lack mitochondria (for example, mature mammalian red blood cells). The multicellular animal Henneguya salminicola is known to have retained mitochondrion-related organelles despite a complete loss of their mitochondrial genome. A large number of unicellular organisms, such as microsporidia, parabasalids and diplomonads, have reduced or transformed their mitochondria into other structures, e.g. hydrogenosomes and mitosomes. The oxymonads Monocercomonoides, Streblomastix, and Blattamonas completely lost their mitochondria.
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