هروئین

Also known as 7,8-Dihydro-4,5-alpha-epoxy-17-methylmorphinan-3,6-alpha-diol diacetate, H, diacetylmorphin, (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate (este), O,O'-Diacetylmorphin, 3,6-Diacetylmorphin, (5α,6α)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate (este), Diacetylmorphin

دی استیل مرفین

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Key facts

Drug.INN: Diamorphine
Drug.Watchedfields: changed
Drug.verifiedrevid: 443854562
Drug.BAN: Diamorphine
Drug.IUPAC_name: (5α,6α)-7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate
Drug.image: Diamorphine2DACS3.svg
Drug.width: 175
Drug.image_class: skin-invert-image
Drug.image2: Heroin-from-xtal-horizontal-3D-balls.png
Drug.image_class2: bg-transparent
Drug.pronounce: Heroin:
Drug.tradename: Diaphin
Drug.dependency_liability: Very high
Drug.addiction_liability: Very high
Drug.routes_of_administration: Intravenous, inhalation, oromucosal, by mouth, intranasal, rectal, intramuscular, subcutaneous, intrathecal
Drug.class: Opioid
Drug.ATC_prefix: N07
Drug.ATC_suffix: BC06

via Wikipedia infobox

Chemical data

Formula: C21H23NO5
Molecular weight: 369.4 g/mol
IUPAC name: [(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl] acetate
SMILES: CC(=O)O[C@H]1C=C[C@H]2[C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)OC(=O)C)CCN3C
InChIKey: GVGLGOZIDCSQPN-PVHGPHFFSA-N
XLogP: 1.5
Polar surface area: 65.1 Å²
H-bond donors: 0
H-bond acceptors: 6
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 3
Molecule type: Small molecule
Indications: heroin dependence, opioid dependence, opioid use disorder

via ChEMBL · EBI

Research

22,916 papers

[Bronchial diseases and heroin use. A systematic review].Revue des maladies respiratoires · 2023Underner M, Perriot J, Peiffer G et al.DOI: 10.1016/j.rmr.2023.09.006
A method of diamorphine (heroin) administration for harm reduction.ReviewHarm reduction journal · 2023Kavanagh ON, Machado TCDOI: 10.1186/s12954-023-00758-1
[Heroin].Revue medicale de Liege · 2013Demaret I, Lemaître A, Ansseau M
Confirmation of recent heroin abuse: Accepting the challenge.ReviewDrug testing and analysis · 2018Maas A, Madea B, Hess CDOI: 10.1002/dta.2244
HEROIN ADDICTION.British medical journal · 1964CHAPPLE PADOI: 10.1136/bmj.2.5425.1662-a
HEROIN ADDICTS.British medical journal · 1964GLATT MMDOI: 10.1136/bmj.1.5390.1116-c
Supervised Injectable Heroin: A Clinical Perspective.ReviewCanadian journal of psychiatry. Revue canadienne de psychiatrie · 2017Bell J, Waal RV, Strang JDOI: 10.1177/0706743716673966
Patients' satisfaction with heroin-assisted treatment: a qualitative study.Harm reduction journal · 2023Ellefsen R, Wüsthoff LEC, Arnevik EADOI: 10.1186/s12954-023-00808-8

via PubMed

Wikidata facts

Has part: hydrogen
Mass: 369.158
Image: Heroin paraphernalia.jpg
Has use: medication

Show 8 more facts

Commons category: Heroin
topic's main category: Category:Heroin
chemical formula: C₂₁H₂₃NO₅
subject has role: narcotic
canonical SMILES: CC(=O)OC1C=CC2C3CC4=C5C2(C1OC5=C(C=C4)OC(=O)C)CCN3C
isomeric SMILES: CC(=O)O[C@H]1C=C[C@H]2[C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)OC(=O)C)CCN3C
melting point: 170
different from: Heroína Island

Sources (9)

via Wikidata · CC0