oligodendroglioma
Oligodendrogliomas are a type of glioma that are believed to originate from the oligodendrocytes of the brain or from a glial precursor cell. They occur primarily in adults (9.4% of all primary brain and central nervous system tumors) but are also found in children (4% of all primary brain tumors). With a 0.2 incidence rate out of 100,000 adults, oligodendrogliomas comprise approximately 5% of all central nervous system tumors.
Key facts
- Medical condition (new).caption
- Micrograph of an oligodendroglioma showing the characteristic branching, small, chicken wire-like blood vessels and fried egg-like cells, with clear cytoplasm and well-defined cell borders. H&E stain.
- Medical condition (new).field
- Neuro-oncology, neurosurgery
- Medical condition (new).onset
- Between ages 35 and 44
- Medical condition (new).prognosis
- Five-year survival rate: 74.1%
- Medical condition (new).frequency
- ~1,217 new diagnoses per year (United States)
- Medical condition (new).name
- Oligodendroglioma
- Medical condition (new).image
- Oligodendroglioma1_high_mag.jpg
via Wikipedia infobox
Research
6,854 papersArticle
10 sectionsContents
- Signs and symptoms
- Cause
- Diagnosis
- Microscopic appearance
- Histopathological grading
- Molecular genetics
- Treatment
- Prognosis
- References
- External links
Oligodendrogliomas are a type of glioma that are believed to originate from the oligodendrocytes of the brain or from a glial precursor cell. They occur primarily in adults (9.4% of all primary brain and central nervous system tumors) but are also found in children (4% of all primary brain tumors). With a 0.2 incidence rate out of 100,000 adults, oligodendrogliomas comprise approximately 5% of all central nervous system tumors.
==Signs and symptoms== Oligodendroglioma arise mainly in the frontal lobe and in 50–80% of cases, the first symptom is the onset of seizure activity without any prior symptoms . Headaches associated with increased intracranial pressure are also common in individuals with oligodendroglioma. Depending on the location of the tumor, many different neurological and neuropsychological deficits can be induced, including, but not limited to, visual loss, motor weakness, cognitive decline, and anxiety. A computed tomography (CT) or magnetic resonance imaging (MRI) scan is necessary to characterize tumor size, location, and hetero- or homogeneity. Final diagnosis relies on biopsy and histopathologic examination of the tumor mass.