HTR2A
Sign in to saveAlso known as 5-HT2A, HTR2, 5-hydroxytryptamine receptor 2A
protein-coding gene in the species Homo sapiens
Gene data
HTR2A- Name
- 5-hydroxytryptamine receptor 2A
- Type
- protein-coding
- Position
- 46,831,546–46,897,076 (−)
- Aliases
- 5-HT2A, HTR2
- Ensembl
- ENSG00000102468
- RefSeq RNA
- NM_000621.5, NM_001165947.5, NM_001378924.1
- RefSeq protein
- NP_000612.1, NP_001159419.2, NP_001365853.1
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
5-hydroxytryptamine receptor 2A
- Symbol
- HTR2A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:46,831,546-46,897,091
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- 5ht2a.jpg
Show 6 more facts
- HomoloGene ID
- 68073
- exact match
- identifiers.org/ncbigene/3356
- genomic end
- 47471169
- genomic start
- 46831546
- cytogenetic location
- 13q14.2
- Commons category
- 5-hydroxytryptamine receptor 2A
via Wikidata · CC0