Skip to content
GeneQ14891424· pop 15· linked from 2,320 articles

Also known as 5-HT2A, HTR2, 5-hydroxytryptamine receptor 2A

protein-coding gene in the species Homo sapiens

Gene data

HTR2A
Name
5-hydroxytryptamine receptor 2A
Type
protein-coding
Position
46,831,546–46,897,076 (−)
Aliases
5-HT2A, HTR2
RefSeq RNA
NM_000621.5, NM_001165947.5, NM_001378924.1
RefSeq protein
NP_000612.1, NP_001159419.2, NP_001365853.1

This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

via MyGene.info

Gene · Ensembl

5-hydroxytryptamine receptor 2A

Symbol
HTR2A
Biotype
Protein coding
Organism
Homo sapiens
Location
13:46,831,546-46,897,091
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
5ht2a.jpg
Show 6 more facts
HomoloGene ID
68073
genomic end
47471169
genomic start
46831546
cytogenetic location
13q14.2
Commons category
5-hydroxytryptamine receptor 2A
Sources (5)

via Wikidata · CC0

Connections

Categories