asenapine
Sign in to saveAsenapine, sold under the brand name Saphris among others, is an atypical antipsychotic medication used to treat schizophrenia and acute mania associated with bipolar disorder as well as the medium to long-term management of bipolar disorder.
Research
574 papersvia PubMed
Clinical Trials
49 registered- PHASE3COMPLETEDEfficacy and Safety of Asenapine Compared With Olanzapine in Patients With Persistent Negative Symptoms of Schizophrenia (25543)(COMPLETED)(P05817)Organon and Co · NCT00212836
- PHASE2/PHASE3COMPLETEDBioequivalence Fasting Study in PatientsAmneal Pharmaceuticals, LLC · NCT02072954
- PHASE3COMPLETED6-week Trial of the Efficacy and Safety of Asenapine Compared to Placebo in Participants With an Acute Exacerbation of Schizophrenia (P06124)Organon and Co · NCT01098110
- PHASE3COMPLETEDLong-Term Safety Extension Trial of Asenapine in Bipolar 1 Disorder Participants Who Completed Protocol P05691 (P05692)Forest Laboratories · NCT01395992
- COMPLETEDAn Observational Modified Prescription-event Monitoring Study of Asenapine (Sycrest)Professor Saad Shakir · NCT01765127
- COMPLETEDPost-Authorization Safety Surveillance Study of Asenapine in Participants With Bipolar Disorder (P08307)Organon and Co · NCT01495741
Wikidata facts
Show 2 more facts
- World Health Organisation international non-proprietary name
- asenapine
- defined daily dose
- 20
via Wikidata · CC0
~9 min read
Article
10 sectionsContents
- Medical uses
- Schizophrenia
- Bipolar disorder
- Adverse effects
- Discontinuation
- Pharmacology
- Pharmacodynamics
- Notes
- References
- External links
Asenapine, sold under the brand name Saphris among others, is an atypical antipsychotic medication used to treat schizophrenia and acute mania associated with bipolar disorder as well as the medium to long-term management of bipolar disorder.
It was chemically derived via altering the chemical structure of the tetracyclic (atypical) antidepressant, mianserin.
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Categories
5-HT1A agonistsAlpha-2 blockersAtypical antipsychoticsChemical articles with multiple CAS registry numbersChemical articles with multiple ChEBIsChemical articles with multiple PubChem CIDsChemicals using indexlabelsChloroarenesDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrug has EMA linkDrugs developed by AbbVieDrugs developed by Merck & Co.Drugs developed by Schering-PloughDrugs with non-standard legal statusECHA InfoCard ID from WikidataHeterocyclic compounds with 4 ringsMultiple chemicals in Infobox drugNitrogen heterocyclesOxepinesTertiary amines